pentobarbital will minimize the level or influence of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will lower the extent or outcome of isavuconazonium sulfate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will lessen the extent or effect of capivasertib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Powerful or reasonable CYP3A inducers reduce capivasertib publicity, which may minimize efficacy.
pentobarbital will minimize the extent or outcome of duvelisib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Coadministration with a solid CYP3A inducer decreases duvelisib place underneath the curve (AUC), which can minimize duvelisib efficacy.
pentobarbital will lower the level or effect of conjugated estrogens by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will reduce the extent or result of alfentanil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unknown.
pentobarbital will reduce the extent or effect of diazepam buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of. Solid or reasonable CYP3A4 inducers may perhaps enhance level of diazepam elimination; thus, efficacy of diazepam can be reduced.
pentobarbital will lower the extent or outcome of etravirine by affecting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Keep an eye on.
Contraindicated (1)pentobarbital will reduce the level or outcome of lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with sturdy CYP3A4 inducers can lead to decreased serum concentrations and loss of antimalarial efficacy
Pentobarbital has long been employed or considered instead to the barbiturate sodium thiopental used for capital punishment by lethal injection in The usa when that drug became unavailable.[sixteen] In 2011 the U.S. maker of sodium thiopental stopped output, and importation with what type of drug is nembutal the drug proved unattainable.
pentobarbital increases levels of vortioxetine by increasing metabolism. Modify Therapy/Observe Carefully. Consider raising the vortioxetine dose when coadministered with powerful CYP inducers for >14 times; to not exceed 3 occasions primary vortioxetine dose.
pentobarbital will minimize the extent or result of elagolix by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
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